Hepcinat® LP

Ledipasivir + Sofosbuvir

What is Hepcinat-LP and what is it used for?

Hepcinat-LP is a medication used to treat chronic hepatitis C virus (HCV) infection in adults. It contains two active ingredients, Sofosbuvir and Ledipasvir, which work together to inhibit the replication of the HCV virus in the body. This medication is taken orally and has been shown to be highly effective in curing HCV infection in most patients.

How does Hepcinat-LP work?

Hepcinat-LP contains two active ingredients, Sofosbuvir and Ledipasvir. Sofosbuvir is a nucleotide analog inhibitor that works by blocking the HCV RNA polymerase enzyme, which is necessary for the replication of the virus. Ledipasvir is an NS5A inhibitor that works by blocking a protein needed for the virus to replicate and assemble.

What is the recommended dosage of Hepcinat-LP?

The recommended dosage of Hepcinat-LP is one tablet taken orally once daily with or without food. The duration of treatment varies depending on the severity of the HCV infection and other factors, but typically ranges from 8 to 24 weeks.

Are there any side effects associated with Hepcinat-LP?

Like all medications, Hepcinat-LP may cause side effects in some patients. The most common side effects include headache, fatigue, nausea, diarrhea, and insomnia. More serious side effects are rare but may include allergic reactions, liver problems, and depression.

Can Hepcinat-LP be taken during pregnancy or breastfeeding?

Hepcinat-LP is not recommended for use during pregnancy or breastfeeding. Women who are pregnant or breastfeeding should discuss the risks and benefits of this medication with their doctor before taking it.

Can Hepcinat-LP interact with other medications?

Hepcinat-LP may interact with certain medications, including some antacids, anti-seizure medications, and HIV medications. Patients should inform their doctor of all medications they are taking before starting treatment with Hepcinat-LP.

Is Hepcinat-LP covered by insurance in the UK?

Hepcinat-LP is covered by the NHS in the UK for patients who meet certain eligibility criteria, including having a confirmed diagnosis of chronic HCV infection and meeting certain liver function tests.

How effective is Hepcinat-LP in treating HCV infection?

Hepcinat-LP has been shown to be highly effective in treating HCV infection in most patients. Clinical studies have reported cure rates of over 90% in patients with HCV genotype 1, the most common genotype in the UK.

Can Hepcinat-LP be used to treat other viral infections?

Hepcinat-LP is specifically indicated for the treatment of chronic HCV infection and is not recommended for use in treating other viral infections.

How can patients access Hepcinat-LP in the UK?

Patients who have been diagnosed with chronic HCV infection and meet certain eligibility criteria may be able to access Hepcinat-LP through the NHS. Patients should discuss their treatment options with their doctor and may be referred to a specialist for further evaluation and treatment.

What are known local names of the medication?

• Sofosbuvir/Ledipasvir
• Hepcvir L
• Ledviclear
• Hepcinat Plus
• Velasof
• Twinvir L
• Ledifos
• MyHep LVIR
• Resof L
• Hepcfix L